Niacinamide is a form of Vitamin-B3 or Niacin. The topical version of Niacinamide is formulated in a water-alcohol base so that it can penetrate the skin more easily. The role of Topical Niacinamide in acne treatment is the reduction of inflammation and redness that occurs in most acne lesions. Niacinamide is an effective topical anti-inflammatory agent that has mild exfoliating action, enabling the skin to shed old skin cells and prevent pore blockage. The mild exfoliating action of niacinamide is attributed to its ability to speed up the differentiation or cell division of keratinocytes. This acne medication also acts as a mild moisturizer that increases the ceramide and free fatty acids in the skin. Topical niacinamide can also mildly reduce the amount of sebum on the oil gland. Some people use topical niacinamide as a very safe skin lightening agent.
Precautions and Side Effects:
Topical Niacinamide can be used by pregnant women and is safe during pregnancy. This acne treatment product is not intended to be used on children.
No adverse side effects. Mild exfoliation, lightening of the skin
Data demonstrate that 4% nicotinamide gel is of comparable efficacy to 1% clindamycin gel in the treatment of acne vulgaris. Because topical clindamycin, like other antimicrobials, is associated with the emergence of resistant microorganisms, nicotinamide gel is a desirable alternative treatment for acne vulgaris.
Topical niacinamide is available in cream, lotion, or gel form. Niacinamide concentration ranges from 2% to 5% by weight.