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Home / Acne Treatment / Acne Treatment with Adapalene

Acne Treatment with Adapalene


  This acne medication is chemically related to Vitamin-A, which belongs to a family of compounds known as Retinoids. The action of Adapalene on the skin is similar to Tretinoin. It promotes the peeling of the skin and renewal of skin cells at a faster rate. Adapalene is less irritating than Tretinoin (Retinoic Acid). This anti-acne product also has some mild anti-inflammatory action and can be used together with benzoyl peroxide. Other retinoids like Tretinoin cannot be used with benzoyl peroxide because it becomes too irritating on the skin.

Precautions and Side Effects:

Do not use adapalene without consulting your doctor if you are pregnant or could become pregnant during acne treatment. This acne medication is not intended to be used on children.
Dryness, redness, and mild peeling of the skin.


Adapalene gel 0.1% applied once daily was significantly more effective in reducing acne lesions and was better tolerated than tretinoin gel 0.025% in the treatment of acne vulgaris.

This study showed that a majority of patients preferred adapalene 0.1% gel over tretinoin 0.025% cream and that it caused significantly less skin irritation.

Product Information:

Adapalene is topically applied to the skin. This anti-acne product is available in cream or gel form at 0.1% to 0.3% concentration

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